June 2025: BIO attendees, non-hallucinogenic neurotherapeutics gain traction, AI-driven cancer predictions advance, and expansion to UCSF and Berkeley


Hey, this is Michael from The Bioentrepreneurs: Stanford. Each month, I bring you key updates and exclusive insights straight from the teams driving innovation across Stanford's life sciences ecosystem.

Here's what's happening in June 2025:

Xylo Bio

Velocity Bio

TwoStep Therapeutics

  • Kicked off Series A fundraising! − The proceeds will enable TwoStep to complete two value-inflection clinical trials for their targeted drug conjugate and radioligand therapy programs.

  • Will be attending the 2025 BIO International Convention in Boston and is now live on the BIO Partnering platform. They would love to connect!

PyrAmes

Phinomics

  • Starting with bladder cancer, achieved > 92% prognostic accuracy predicting disease recurrence—dramatically surpassing clinical standards—and uncovered novel therapeutic targets now entering validation.

  • Identified novel therapeutic targets in urologic cancers and are strategically exploiting them in disease-relevant model systems.

  • Recently expanded their AI/ML pipelines to integrate chromosomal instability signals with molecular network reconstruction, enabling deeper insights into disease mechanisms and the identification of actionable molecular drivers for clinical intervention —including degenerative disorders, proliferative diseases, cellular senescence, and genome instability syndromes.

  • Hiring: Senior Scientist in Target Discovery and Tissue Analysis

    • The ideal candidate has experience processing tissue samples including organoids and executing quantitative, multi-parametric analyses to identify disease-relevant targets.

    • This is a unique opportunity to help translate novel biology into therapeutic reality, working at the intersection of cutting-edge genomics, machine learning, and drug discovery.

    • To learn more or apply, reach out to us at [email protected] or message Massa directly.

Parallel Health

Logomix

  • Strong Funding Milestone: secured over $23 million to date, underpinning Logomix’s ambitious expansion plans into US markets and further development of transformative cell therapies.

  • Strategic Collaborations with MIT and Emerging Biotechs: initiated high-impact research partnerships, including an innovative collaboration with Prof. Ron Weiss’s lab at MIT, focused on regenerative medicine and next-generation cell therapies. This work complements their strategic alliances with emerging biotech companies in the US.

  • AI-Driven Cell Engineering: launched early collaborations leveraging Logomix's engineered cell lines with a leading AI x Biotech company, integrating machine learning to predict and enhance therapeutic outcomes. Actively exploring further AI partnerships to drive innovation at the intersection of AI and regenerative medicine.

  • ISSCR 2025 Oral Presentation: Yas, their scientific lead, was selected to deliver an oral presentation at the ISSCR Annual Meeting (June 2025), highlighting breakthroughs from Logomix's genome editing platform and its applications in stem cell therapies.

  • Expanding Leadership Team: welcomed Dr. Ramy Ibrahim (former Chief Medical Officer at the Parker Institute for Cancer Immunotherapy) and Dr. Mitchell Finer (co-founder and former President of R&D at ElevateBio) as senior scientific advisors. Their deep expertise in genome editing, iPSC-derived therapies, and clinical translation will help guide Logomix’s strategy as they advance their Geno-Writing™ platform toward transformative, off-the-shelf cell therapies.

Illuminant Surgical

  • Completed preliminary accuracy studies that shows 2x accuracy compared to existing systems on the market in end-to-end placement. This was achieved after a thorough re-design of optical and instrument calibration.

  • Dr. James Hu, MD, presented Skylight, the company’s platform for surgical access, at the 13th Annual Global Spine Congress in Rio de Janeiro. Thousands of attendees with leaders in international spine care were in attendance.

  • Their software team is leading a workshop and presenting a poster at this year’s SIGGRAPH Conference in Vancouver, the world’s premier graphics conference.

  • The cofounders, Eldrick and James, are giving the keynote at this year’s Stanford Mussallem Center for Biodesign Health Technology Showcase. Register here.

Dr. James Hu, MD presenting Skylight at the 13th Annual Global Spine Congress in Rio de Janeiro.

Generation Lab

  • Top-tier seed funding: Recently closed a fresh round of funding, ranking in the top 1% of all seed-stage raises—a signal of investor confidence in the future of preventative aging diagnostics.

  • Achieved substantial commercial traction less than 10 months post-launch: Signed 125+ clinics worldwide since launching SystemAge, the first test to measure biological and organ-specific aging.

  • SystemAgeTM Test has demonstrated over 99.9% accuracy across tens of thousands of users.

  • Generated over 300 million data points on human aging, now fueling new insights into preventative care.

  • Recent breakthrough findings:

    • Ability to detect signals before symptoms—a major step toward proactive, personalized medicine.

    • Data shows 70% of individuals are biologically older than their chronological age—largely due to lifestyle, environmental, and stress-related factors. Founders are aging 1.5X faster than investors.

    • Can now quantify the efficacy of health and longevity interventions

Foldscope Instruments

  • Featured in a recent Quanta Magazine interview with its co-inventor Manu Prakash, who reflects on the role of curiosity and observation in science. Developed as a low-cost tool for global health and education, Foldscope has been used to diagnose diseases like malaria in resource-limited settings. “Observation is a practice, and if you don’t practice, you lose it,” Prakash explains.

DropXcell

  • Actively raising a Seed round of capital to fund their goal of being the leading technology for multispecific antibody discovery. By quantitatively screening millions of antibodies for drug function, training AI models on huge quantitative data sets, and repeating, their platform has the potential to create the next generation of therapies for cancer, autoimmune disease, GPCR targets, and more—all in less than half the time of traditional discovery processes.

  • Will be at The Bullpen at the 2025 BIO International Convention in Boston 6/15 – 6/18 to discuss investment and partnership opportunities.

  • For more information, please reach out to [email protected]. They are seeking VCs, angels, and family offices to commit funds by end of July.

Where you can find me this month:

Thursday, June 5th - Stanford Biodesign Health Technology Showcase 2025  (Stanford)

The Bioentrepreneurs Expansion Has Begun!

We’re actively expanding to include life sciences startups founded by alum, students, faculty, and researchers from UCSF and Berkeley. If you're building something bold, we'd love to hear from you! 

Until next time,

Michael Snyder [LinkedIn]

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